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What is Exjade?

The generic name of Exjade is Deferasirox.  Exjade is used to treat Chronic Iron Overload in:

• Patients from 6 years of age who have beta-thalassemia major and receive frequent blood transfusions.
• Children aged 2 to 5 years with a beta-thalassemia major who receives frequent blood transfusions, when deferoxamine cannot be used.
• Patients from 2 years of age with a beta-thalassemia major who receive infrequent blood transfusions, when deferoxamine cannot be used or is inadequate.
• Patients from 2 years of age who suffer from other types of anemia and who receive blood transfusions when deferoxamine cannot be used or is inadequate.
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What is Exjade Used For?

Exjade is used to treat Ongoing High Levels Of Iron in the body caused by multiple blood transfusions. Exjade is also used to treat high levels of iron in people with a Certain Blood Disorder who do not require blood transfusions. It works by binding to iron, allowing the body to pass extra iron out in the stool.

How To Use Exjade?

• Stir the tablet(s) into the water, orange juice, or apple juice until the tablets have completely dissolved into the liquid.
• If your dose is less than 1 gram, stir the tablets into about 1/2 cup (3.5 ounces/100 milliliters) of liquid.
• If your dose is more than 1 gram, use about 1 cup (7 ounces/200 milliliters) of liquid.
• Drink all of the mixtures right away, then add more liquid to the empty container and stir to get any drug that may remain.

Why Exjade is Prescribed?

Exjade is a prescription medicine used to treat the Symptoms Of Iron Overload in the blood (Transfusional Hemosiderosis, Nontransfusion-Dependent Thalassemia). Exjade may be used alone or with other medications. It works by Binding To Iron, allowing the body to pass extra iron out in the stool. It is not known if Exjade is safe and effective in children younger than 2 years of age.

What Conditions Does Exjade Treat?

Exjade is used to treat iron overload caused by Blood Transfusions In Adults and children at least 2 years old. Exjade is also used to treat chronic iron overload syndrome caused by a Genetic Blood Disorder (non-transfusion-dependent thalassemia) in adults and children who are at least 10 years old. Exjade binds to iron and removes it from the bloodstream.

Exjade Dosage

• The usual recommended starting dose of Exjade is 10 mg to 30 mg per kilogram of body weight per day, depending on the individual.
• Your dosage may need to be lowered or your treatment may need to be stopped if you get certain side effects.
• Do not increase your dose or use this drug more often or for longer than prescribed.
• Exjade should be taken once daily at about the same time each day. It should be taken on an empty stomach and at least 30 minutes before the first meal of the day.

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Side Effects of Exjade:

Common side effects include but are not limited to:

• Hives
• Difficulty breathing
• Swelling of your face, lips, tongue, or throat
• Fever
• Sore throat
• Burning in your eyes
• Skin pain
• Red or purple skin rash that spreads and causes blistering and peeling
• Problems with vision or hearing
• Little or no urination
• Swelling in your feet or ankles
• Tiredness
• Shortness of breath
• Nausea
• Upper stomach pain
• Itching
• Loss of appetite
• Dark urine
• Clay-colored stools
• Yellowing of the skin or eyes (jaundice)
• Chills
• Mouth sores
• Skin sores
• Pale skin
• Easy bruising
• Unusual bleeding
• cold hands and feet
• Lightheadedness
• Bloody or tarry stools
• Coughing up blood
• Vomit that looks like coffee grounds
• Nausea
• Vomiting
• Stomach pain
• Diarrhea
• Skin rash

Cautions To Take Exjade:

You should not use Exjade if you are allergic to it or any of its ingredients
You should not use Exjade if you have:

• Severe liver or kidney disease
• Advanced cancer
• A bone marrow disorder
• Low levels of platelets in your blood

Tell your doctor if you have ever had:

• Kidney disease
• Liver disease
• Anemia (low red blood cells)
• Cancer (especially blood cell cancer such as leukemia)
• A stomach ulcer
• Stomach or intestinal bleeding
• Vision or hearing problems
• A weak immune system is caused by disease (such as cancer, hiv, or aids), or by receiving steroids, chemotherapy, or radiation.
• Exjade can make birth control pills less effective. Ask your doctor about using nonhormonal birth control to prevent pregnancy.
• You should not breastfeed while using Exjade.